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Genetic Engineering and Molecular Studies of In...
40,99 € *
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This book reveals some details of research done at Marshall University, USA, involving functional aspects of pancreatic beta cells in several experimental models: avian, transgenic mice, and beta-cell lines. In this book you will gain some knowledge of genetic engineering approaches to improve beta-cell insulin secretion which could be applied to manage models and cases of diabetes mellitus. This work is presented as three separate chapters. The first chapter aims to gain an understanding of the expression pattern of CaBP28k in the chicken pancreas and to explore its spatial relationships with insulin in beta cells. The second chapter is to identify the influence of CaBP28k-ablation on the dynamics of [Ca2+]i in response to glucose stimulation in murine beta cells of CaBP28k-KO mice pancreatic islets and wildtype islets. The third chapter is an attempt to elucidate the genomic and non-genomic effects of in vitro CaBP28k-ablation in a cultured beta-cell line. It highlights the effects on the gene expression profile and insulin secretory responses from cultured rat insulinoma cell lines using antisense oligonucleotides transfection.

Anbieter: buecher
Stand: 05.04.2020
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Re-entry and Planetary Entry Physics and Techno...
128,49 € *
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Re-entry and Planetary Entry Physics and Technology ab 128.49 € als Taschenbuch: I / Dynamics Physics Radiation Heat Transfer and Ablation Applied Physics and Engineering. Softcover reprint of the original 1st ed. 1968. Aus dem Bereich: Bücher, Wissenschaft, Technik,

Anbieter: hugendubel
Stand: 05.04.2020
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Neurosurgical Operative Atlas
156,99 € *
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A state-of-the-art guide to evolving functional neurosurgery approaches from world-renowned innovators Functional neurosurgery focuses on improving the lives of patients with epilepsy, movement disorders, pain, and psychiatric illnesses. In recent years, approaches ranging from open surgery to minimally invasive techniques have been leveraged to improve daily functioning and quality of life in people struggling with painful, highly disruptive, and/or treatment-resistant symptoms. These approaches focus on reducing or eliminating seizures, alleviating pain, decreasing abnormal movements or lessening debilitating symptoms associated with specific psychiatric disorders. Neurosurgical Operative Atlas: Functional Neurosurgery, Third Edition, by renowned functional neurosurgeons Robert Gross, Nicholas Boulis, and esteemed contributors reflects the latest advances in functional and stereotactic neurosurgical approaches. The entire atlas has been streamlined and updated with new content, including the use of stereotactic surgery to treat obsessive compulsive disorder, Tourette syndrome, and major depression. Key Highlights A full spectrum of epilepsy treatment techniques, including intracranial monitoring with stereo-electroencephalography, selective amygdalohippocampectomy, MRI-guided stereotactic laser ablation, vagus nerve stimulation, and more Deep brain stimulation (DBS) for Parkinson's disease, tremor, dystonia, epilepsy and medically intractable pain syndromes, with in-depth implantation guidance The use of neurosurgical and interventional techniques to treat pain including percutaneous ablation, peripheral nerve stimulation, spinal cord and motor cortex stimulators, and pumps More than 300 high quality color illustrations detail anatomy and surgical procedures This is the ultimate guide on functional neurosurgery for managing a wide range of incapacitating neurological conditions. Neurosurgical residents, fellows, and veteran neurosurgeons specializing in this rapidly evolving subspecialty will find this state-of-the-art book invaluable - reading it cover to cover will ultimately benefit patients. Series description The American Association of Neurological Surgeons and Thieme have collaborated to produce the third edition of the acclaimed Neurosurgical Operative Atlas series. Edited by leading experts in the field, the series covers the entire spectrum of neurosurgery in five volumes. In addition to Functional Neurosurgery, the series also features: Spine and Peripheral Nerves, edited by Christopher E. Wolfa and Daniel K. Resnick Vascular Neurosurgery, edited by R. Loch Macdonald Neuro-Oncology, edited by Behnam Badie and Mike Y. Chen Pediatric Neurosurgery, edited by James Tait Goodrich and Robert F. Keating Robert E. Gross, MD, PhD, is MBNA Bowman Chair in Neurosurgery & Professor, Emory University Department of Neurosurgery; Director and Co-Founder, Emory Neuromodulation and Technology Innovation Center (ENTICe); Director, Translational Neuro-Engineering Laboratory; Director, Emory MD/PhD Program; and Director, Stereotactic, Functional and Epilepsy Neurosurgery, Atlanta, Georgia, USA. Nicholas M. Boulis, MD, is Associate Professor, Emory University Department of Neurosurgery; and Director, Gene and Cell Therapy for Neurorestoration Laboratory, Atlanta, Georgia, USA. An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.

Anbieter: buecher
Stand: 05.04.2020
Zum Angebot
Neurosurgical Operative Atlas
156,99 € *
ggf. zzgl. Versand

A state-of-the-art guide to evolving functional neurosurgery approaches from world-renowned innovators Functional neurosurgery focuses on improving the lives of patients with epilepsy, movement disorders, pain, and psychiatric illnesses. In recent years, approaches ranging from open surgery to minimally invasive techniques have been leveraged to improve daily functioning and quality of life in people struggling with painful, highly disruptive, and/or treatment-resistant symptoms. These approaches focus on reducing or eliminating seizures, alleviating pain, decreasing abnormal movements or lessening debilitating symptoms associated with specific psychiatric disorders. Neurosurgical Operative Atlas: Functional Neurosurgery, Third Edition, by renowned functional neurosurgeons Robert Gross, Nicholas Boulis, and esteemed contributors reflects the latest advances in functional and stereotactic neurosurgical approaches. The entire atlas has been streamlined and updated with new content, including the use of stereotactic surgery to treat obsessive compulsive disorder, Tourette syndrome, and major depression. Key Highlights A full spectrum of epilepsy treatment techniques, including intracranial monitoring with stereo-electroencephalography, selective amygdalohippocampectomy, MRI-guided stereotactic laser ablation, vagus nerve stimulation, and more Deep brain stimulation (DBS) for Parkinson's disease, tremor, dystonia, epilepsy and medically intractable pain syndromes, with in-depth implantation guidance The use of neurosurgical and interventional techniques to treat pain including percutaneous ablation, peripheral nerve stimulation, spinal cord and motor cortex stimulators, and pumps More than 300 high quality color illustrations detail anatomy and surgical procedures This is the ultimate guide on functional neurosurgery for managing a wide range of incapacitating neurological conditions. Neurosurgical residents, fellows, and veteran neurosurgeons specializing in this rapidly evolving subspecialty will find this state-of-the-art book invaluable - reading it cover to cover will ultimately benefit patients. Series description The American Association of Neurological Surgeons and Thieme have collaborated to produce the third edition of the acclaimed Neurosurgical Operative Atlas series. Edited by leading experts in the field, the series covers the entire spectrum of neurosurgery in five volumes. In addition to Functional Neurosurgery, the series also features: Spine and Peripheral Nerves, edited by Christopher E. Wolfa and Daniel K. Resnick Vascular Neurosurgery, edited by R. Loch Macdonald Neuro-Oncology, edited by Behnam Badie and Mike Y. Chen Pediatric Neurosurgery, edited by James Tait Goodrich and Robert F. Keating Robert E. Gross, MD, PhD, is MBNA Bowman Chair in Neurosurgery & Professor, Emory University Department of Neurosurgery; Director and Co-Founder, Emory Neuromodulation and Technology Innovation Center (ENTICe); Director, Translational Neuro-Engineering Laboratory; Director, Emory MD/PhD Program; and Director, Stereotactic, Functional and Epilepsy Neurosurgery, Atlanta, Georgia, USA. Nicholas M. Boulis, MD, is Associate Professor, Emory University Department of Neurosurgery; and Director, Gene and Cell Therapy for Neurorestoration Laboratory, Atlanta, Georgia, USA. An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.

Anbieter: buecher
Stand: 05.04.2020
Zum Angebot
Re-entry and Planetary Entry Physics and Techno...
128,49 € *
ggf. zzgl. Versand

Re-entry and Planetary Entry Physics and Technology ab 128.49 EURO I / Dynamics Physics Radiation Heat Transfer and Ablation Applied Physics and Engineering. Softcover reprint of the original 1st ed. 1968

Anbieter: ebook.de
Stand: 05.04.2020
Zum Angebot
Genetic Engineering and Molecular Studies of In...
59,00 € *
ggf. zzgl. Versand

This book reveals some details of research done at Marshall University, USA, involving functional aspects of pancreatic beta cells in several experimental models: avian, transgenic mice, and beta-cell lines. In this book you will gain some knowledge of genetic engineering approaches to improve beta-cell insulin secretion which could be applied to manage models and cases of diabetes mellitus. This work is presented as three separate chapters. The first chapter aims to gain an understanding of the expression pattern of CaBP28k in the chicken pancreas and to explore its spatial relationships with insulin in beta cells. The second chapter is to identify the influence of CaBP28k-ablation on the dynamics of [Ca2+]i in response to glucose stimulation in murine beta cells of CaBP28k-KO mice pancreatic islets and wildtype islets. The third chapter is an attempt to elucidate the genomic and non-genomic effects of in vitro CaBP28k-ablation in a cultured beta-cell line. It highlights the effects on the gene expression profile and insulin secretory responses from cultured rat insulinoma cell lines using antisense oligonucleotides transfection.

Anbieter: Dodax
Stand: 05.04.2020
Zum Angebot
Bioelectrochemical phenomena: electrolysis and ...
79,00 € *
ggf. zzgl. Versand

Over the last decades, applications of irreversible electroporation (IRE) have emerged in biotechnology, food industry, and medicine. IRE uses a series of microsecond electric pulses that permanently open cell membranes and lead to cell death. The goal of this book is to address certain aspects of two major IRE applications: disinfection and tissue ablation in the treatment of diseases such as cancer. In relation to disinfection, I discuss IRE for sterilization of drugs, and using IRE for storage of perishable products. In relation to tissue ablation, I present a statistical model IRE treatment planning, and a new method for real-time control of IRE procedure. During the research on the real-time control of IRE in tissues, we realized that it has value beyond the original intended application - it may be used for generation of low cost electric energy. Theoretical analyses and emerging application discussed in this book should be especially useful to professionals in the Biomedical and Food Engineering fields, or anyone who is interested in the field of bioelectricity.

Anbieter: Dodax
Stand: 05.04.2020
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Parallel Diffractive Multi-beam Ultrafast Laser...
68,00 € *
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Ultrafast lasers have been widely employed for material micro/nano processing with little thermal damage. Due to the ultra high intensity of ultrashort pulses, nonlinear absorption can be induced at the focus leading to highly localised material ablation or modification. This is now opening up applications ranging from integrated optics, through multi-photon induced refractive index engineering to precision surface micro-structuring. To ensure the non-thermal processing, input pulse energy must be kept around micro-joule level. However, running at kilohertz repetition rate, many ultrafast laser systems can provide milli-joule level output. Therefore, significant energy attenuation causes a great deal of energy loss. With this limitation in mind, a multi-beam ultrafast laser processing, where the milli-joule output is split into many desired diffracted beams, is proposed in this book. The multi-beam patterns are generated by phase modulation through a Spatial Light Modulator (SLM) and can be applied in real time with synchronized scanning methods. The results demonstrate high precision parallel ultrafast laser micro/nano fabrication with greatly increased efficiency and throughput.

Anbieter: Dodax
Stand: 05.04.2020
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Nanoparticles by Continuous-wave Laser Ablation...
79,00 € *
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Laser ablation in liquid is becoming an important technique for the generation of nanoparticles (NPs). Until now only pulsed lasers have been used, this is a pioneer work, using high-power, high-brightness continuous-wave (CW) fibre laser ablation in liquid, for the generation of NPs. A mechanism is proposed based on experimental observations, including high-speed imaging and emission spectroscopic analysis of the ablated plume. Three different target materials (Titanium, Nickel and Alpha-aluminium-oxide), submerged in either water or sodium dodecyl sulphate (SDS) solution at various concentrations were used. The characterisation of the generated metal-oxide NPs, in terms of size, size-distribution, shape, chemical composition and phase structure was carried out by UV-Vis photo-spectroscopy, transmission electron microscopy (TEM), high-resolution TEM with energy-dispersive X-rays spectroscopy and X-ray diffraction. This study paves a route towards a new application of CW fibre lasers. The book is useful to engineering students, professional engineers, researchers, academicians and scientists in materials, NPs characterisation, mechanical, laser processing and related disciplines.

Anbieter: Dodax
Stand: 05.04.2020
Zum Angebot